Full description:
Captopril Denk 25 belongs to a class of drugs known as angiotensin conversion enzyme inhibitors (ACE inhibitors). These inhibit ACE, the enzyme involved in the conversion of angiotensin I to angiotensin II. Angiotensin II, a substance produced naturally in the body, binds to the receptors of blood vessels and thus leads to blood vessel constriction. This results in a rise in blood pressure. Captopril prevents the formation of angiotensin II and thus causes relaxation of the blood vessels and a reduction in blood pressure.
Captopril Denk 25 is used
- in the treatment of high blood pressure (hypertension),
- in the treatment of chronic impairment of cardiac performance (cardiac insufficiency).
What Captopril Denk 25 contains:
- The active substance is captopril. Each tablet contains 25 mg captopril.
- The other ingredients are lactose anhydrous, microcrystalline cellulose, maize starch, stearic acid, colloidal anhydrous silica and talc.
Possible side effects:
Like all medicines, this medicine can cause side effects, although not everybody gets them. Stop taking Captopril Denk 25 and seek medical advice immediately,
- if sudden tissue swelling occurs involving the larynx, throat and/or tongue (angioneurotic oedema). You must be admitted to hospital immediately and kept under medical observation for at least 12 to 24 hours;
- in case of excessive hypotension, jaundice or hypersensitivity reactions which may be life-threatening under certain circumstances. Please inform your physician immediately if any of these adverse drug reactions occur suddenly or worsen unexpectedly. Do not under any circumstances continue to take the medication without medical supervision.
Adverse drug reactions that were reported in association with captopril and/ or treatment with another ACE inhibitor are as follows:
Common (may affect up to 1 in 10 people)
- sleep disorders
- distorted sense of taste
- dizziness
- dry irritating (non-productive) cough
- shortness of breath
- nausea
- vomiting
- upset stomach
- stomach pain
- diarrhea
- constipation
- dryness of mouth
- itchiness with or without rash
- rash
- alopecia
Uncommon (may affect up to 1 in 100 people)
- rise in heart rate
- heart rhythm disturbances
- angina pectoris
- palpitations
- hypotension
- Raynaud’s syndrome (onset of circulatory disturbances usually occurring in the blood vessels of the finger and caused by contraction of blood vessels)
- facial redness
- paleness
- swelling of the face, lips, tongue, hands and feet
- chest pain
- exhaustion
- malaise
Rare (may affect up to 1 in 1,000 people)
- loss of appetite
- lightheadedness
- headaches
- sensory disturbances
- inflammation of oral mucosa associated with development of mouth ulcers/ aphthae
- renal dysfunction including renal failure
- increased urinary output
- reduced urinary output
- polyuria
Very rare (may affect up to 1 in 10,000 people)
- changes in blood count
- lymph node disease
- autoimmune diseases
- fall in blood sugar level
- rise in serum potassium
- confusion
- depression
- circulatory disturbances of the brain including stroke and fainting
- blurred vision
- cardiac arrest
- shock
- spasmodic bronchial constriction
- common cold
- allergic inflammation of the alveoli/pneumonia
- inflammation of the tongue
- gastric ulcer
- inflammation of the pancreas
- impaired liver function and cholestasis (including jaundice)
- hepatitis including necrosis
- raised liver enzymes and bilirubin values
- urticaria
- photosensitivity
- severe skin reactions
- muscular pain
- joint pain
- nephrotic syndrome
- impotence
- breast enlargement in men
- fever
- some altered laboratory parameters
How to take:
Oral use. Captopril Denk 25 can be taken in-between meals. The tablets should be taken with a little fluid (e.g. a glass of water). The tablet can be divided into 2 equal doses.
