Full description:
Ena-Denk 10 is an ACE inhibitor (angiotensin converting enzyme inhibitor), i.e. an antihypertensive drug that relieves the heart. Ena-Denk 10 is used:
- in the treatment of high blood pressure (hypertension)
- in the treatment of cardiac insufficiency – supplementary to diuretics and, in the event of severe heart insufficiency, to digitalis.
What Ena-Denk 10 contains:
- The active substance is enalapril (as maleate). Each tablet contains 10 mg enalapril maleate.
- The other ingredients are sodium hydrogen carbonate, lactose monohydrate, magnesium stearate, maize starch, talc, iron (III) oxide.
Possible side effects:
Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:
Stop taking this medicine and talk to a doctor straight away, if you notice any of the following:
- swelling of your face, lips, tongue or throat which may cause difficulty in breathing or swallowing
- swelling of your hands, feet or ankles
- if you develop a raised red skin rash (hives).
You should be aware that black patients are at increased risk of these types of reactions. If any of the above happens, stop taking this medicine and talk to a doctor straight away.
When you start taking this medicine you may feel faint or dizzy. If this happens, it will help to lie down. This is caused by your blood pressure lowering. It should improve as you continue to take the medicine. If you are worried, please talk to your doctor.
Other side effects include:
Very common (may affect more than 1 in 10 patients)
- feeling dizzy, weak or sick
- blurred vision
- cough
Common (may affect up to 1 in 10 patients)
- light-headedness due to low blood pressure, changes in heart rhythm, fast heartbeat, angina or chest pain
- headache, depression, fainting (syncope), change in sense of taste
- shortness of breath
- diarrhoea, abdominal pain
- tiredness (fatigue)
- rash, allergic reactions with swelling of the face, lips, tongue or throat with difficulty in swallowing or breathing
- high levels of potassium in the blood, increased levels of creatinine in your blood (both are usually detected by a test)
Uncommon (may affect up to 1 in 100 patients)
- flushing
- sudden fall in blood pressure
- fast or uneven heart beats (palpitations)
- heart attack (possibly due to very low blood pressure in certain high-risk patients, including those with blood flow problems of the heart or brain)
- stroke (possibly due to very low blood pressure in high-risk patients)
- anaemia (including aplastic and haemolytic)
- confusion, sleeplessness or sleepiness, nervousness
- feeling your skin prickling or being numb
- vertigo (spinning sensation)
- ringing in your ears (tinnitus)
- runny nose, sore throat or hoarseness
- asthma-associated tightness in chest
- slow movement of food through your intestine (ileus), inflammation of your pancreas
- being sick (vomiting), indigestion, constipation, anorexia
- irritated stomach (gastric irritations), dry mouth, ulcer
- muscle cramps
- impaired kidney function, kidney failure
- increased sweating
- itching or nettle rash
- hair loss
- generally feeling unwell (malaise), high temperature
(fever)
- impotence
- high level of proteins in your urine (measured in a test)
- low level of blood sugar or sodium, high level of blood urea (all measured in a blood test)
Rare (may affect up to 1 in 1,000 patients)
- ‘Raynaud’s phenomenon’ where your hands and feet may become very cold and white due to low blood flow
- changes in blood values such as a lower number of white and red blood cells, lower haemoglobin, lower number of blood platelets
- bone marrow depression
- swollen glands in neck, armpit or groin
- autoimmune diseases
- strange dreams or sleep problems
- accumulation of fluid or other substances in the lungs (as seen on X-rays)
- inflammation of your nose
- inflammation of the lungs causing difficulty breathing (pneumonia)
- inflammation of the cheeks, gums, tongue, lips, throat
- reduced amount of urine
- rash that looks like targets (erythema multiforme)
- ‘Stevens-Johnson syndrome’ and ‘toxic epidermal necrolysis’ (serious skin conditions where you have reddening and scaling of your skin, blistering or raw sores), exfoliative dermatitis/erythroderma (severe skin rash with flaking or peeling of the skin), pemphigus (small fluid-filled bumps on the skin)
- liver or gallbladder problems such as lower liver function, inflammation of your liver, jaundice (yellowing of the skin or eyes), high levels of liver enzymes or bilirubin (measured in a blood test)
- enlargement of breasts in males (gynaecomastia)
Very rare (may affect up to 1 in 10,000 patients)
- swelling in your intestine (intestinal angioedema)
Not known (frequency cannot be estimated from the available data)
- overproduction of antidiuretic hormone, which causes fluid retention, resulting in weakness, tiredness or confusion
- a symptom complex has been reported which may include some or all of the following: fever, inflammation of the blood vessels (serositis/ vasculitis), muscle pain (myalgia/myositis), joint pain (arthralgia/arthritis). Rash, photosensitivity or other skin manifestations may occur.
How to take:
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
It is very important to continue taking this medicine for as long as your doctor prescribes it.
Do not take more tablets than prescribed.
