Full description:
Amlo-Denk 5 contains the active substance amlodipine and belongs to a group of medicines
called calcium antagonists. Amlo-Denk 5 is used to treat high blood pressure (hypertension) or
a certain type of chest pain called angina, a rare form of which is Prinzmetal’s or variant angina.
In patients with high blood pressure this medicine works by relaxing blood vessels, so that blood
passes through them more easily. In patients with angina Amlo-Denk 5 works by improving
blood supply to the heart muscle which then receives more oxygen and as a result chest pain is
prevented. This medicine does not provide immediate relief of chest pain from angina.
What Amlo-Denk 10 contains:
The active substance is amlodipine. Each tablet contains 12.79 mg amlodipine mesilate 1 H2O,
equivalent to 5 mg amlodipine. The other ingredients are microcrystalline cellulose, calcium
hydrogen phosphate anhydrous, sodium starch glycolate, magnesium stearate [vegetable].
Possible side effects:
side effects, although not everybody gets them.Visit your doctor immediately if you
experience any of the following side effects after taking this medicine.
• Sudden wheeziness, chest pain, shortness of breath or difficulty in breathing
• Swelling of eyelids, face or lips
• Swelling of the tongue and throat which causes great difficulty breathing
• Severe skin reactions including intense skin rash, hives, reddening of the skin over
your whole body, severe itching, blistering, peeling and swelling of the skin,
inflammation of mucous membranes (Stevens Johnson Syndrome, toxic epidermal
necrolysis) or other allergic reactions
• Heart attack, abnormal heart beat
• Inflamed pancreas which may cause severe abdominal and back pain accompanied
with feeling very unwell The following very common side effects have been reported. If
any of these cause you problems or if they last for more than one week, you should
contact your doctor. Very common: may affect more than 1 in 10 people
• Fluid accumulation (oedema)
The following common side effects have been reported. If any of these cause you
problems or if they last for more than one week, you should contact your doctor.
Common: may affect up to 1 in 10 people
• Headache, dizziness, sleepiness (especially at the beginning of treatment)
• Palpitations (awareness of your heart beat), flushing
• Abdominal pain, feeling sick (nausea)
• Altered bowel habits, diarrhoea, constipation, indigestion
• Tiredness, weakness
• Visual disturbances, double vision
• Muscle cramps
• Swollen ankles
Other side effects that have been reported include the following list. If any of these get
serious, or if you notice any side effects not listed in this leaflet, please tell your doctor
or pharmacist. Uncommon: may affect up to 1 in 100 people
• Mood changes, anxiety, depression, sleeplessness
• Trembling, taste abnormalities, fainting
• Numbness or tingling sensation in your limbs; loss of pain sensation
• Ringing in the ears
• Low blood pressure
• Sneezing/running nose caused by inflammation of the lining of the nose (rhinitis)
• Cough
• Dry mouth, vomiting (being sick)
• Hair loss, increased sweating, itchy skin,red patches on skin, skin discolouration
• Disorder in passing urine, increased need to urinate at night, increased number of
times of passing urine
• Inability to obtain an erection; discomfort or enlargement of the breasts in men
• Pain, feeling unwell
• Joint or muscle pain, back pain
• Weight increase or decrease
Rare: may affect up to 1 in 1,000 people
• Confusion
Very rare: may affect up to 1 in 10,000 people
• Decreased numbers of white blood cells, decrease in blood platelets which may result
in unusual bruising or easy bleeding (red blood cell damage)
• Excess sugar in blood (hyperglycaemia)
• A disorder of the nerves which can cause weakness, tingling or numbness
• Swelling of the gums
• Abdominal bloating (gastritis)
• Abnormal liver function, inflammation of the liver (hepatitis), yellowing of the skin
(jaundice), liver enzyme increase which may have an effect on some medical tests
• Increased muscle tension
• Inflammation of blood vessels, often with skin rash
• Sensitivity to light
• Disorders combining rigidity, tremor, and/or movement disorders.
How to take:
Always take this medicine exactly as your doctor has told you. Check with your doctor
or pharmacist if you are not sure. The usual initial dose is 5 mg amlodipine once daily.
The dose can be increased to 10 mg amlodipine once daily. This medicine can be used
before or after food and drinks. You should take this medicine at the same time each
day with a drink of water. Do not take Amlo-Denk 5 with grapefruit juice.
