Full description:
Grani-Denk 1 mg/ml contains a medicine called granisetron. This belongs to a group of medicines called “5-HT3 receptor antagonists” or “anti-emetics”.
Grani-Denk 1 mg/ml is used to prevent or treat nausea and vomiting (feeling and being sick) caused by other medical treatments, such as chemotherapy or radiotherapy for cancer, and by surgery.The solution for injection or infusion is for use in adults and children from 2 years of age.
What Grani-Denk 1 mg/ml contains:
- The active substance is granisetron (as hydrochloride). Each 1 ml ampoule contains 1 mg granisetron as granisetron hydrochloride in a 1 ml sterile concentrate for solution.
- Each 3 ml ampoule contains 3 mg granisetron as granisetron hydrochloride in a 3 ml sterile concentrate for solution.
The other ingredients are sodium chloride, citric acid monohydrate, sodium hydroxide and water for injections.
Possible side effects:
If you notice the following problem you must see a doctor straight away:
- allergic reactions (anaphylaxis). The signs may include swelling of the throat, face, lips and mouth, difficulty in breathing or swallowing.
Other side effects that may be experienced while using this medicine are:
Very common (affects more than 1 user in 10) headache constipation. Your doctor will monitor your condition.
Common (affects 1 to 10 users in 100)
problems sleeping (insomnia) changes in how your liver is working shown by blood tests diarrhoea
Uncommon (affects 1 to 10 users in 1,000)
- skin rashes or an allergic skin reaction or “nettle-rash” or “hives” (urticaria). The signs may include red, raised itchy bumps.
- changes in the heartbeat (rhythm) and changes seen on ECG readings (electrical recordings of the heart)
- abnormal involuntary movements, such as shaking, muscle rigidity and muscle contractions
- Serotonin Syndrome. The signs may include diarrhoea, nausea, vomiting, high temperature and blood pressure, excessive sweating and rapid heartbeat, agitation, confusion, hallucination, shivering, muscles shakes, jerks or stiffness, loss of coordination and restlessness.
How to take:
The injection will be given to you by a doctor or nurse. The dose of Grani-Denk 1 mg/ml varies from one patient to another. It depends on your age, weight, and whether you are being given the medicine to prevent, or treat nausea and vomiting. The doctor will work out how much to give you.
Grani-Denk 1 mg/ml can be given as an injection into the veins (intravenous).
